Evaluation of the expression level of apoptosis and ferroptosis cell death pathways genes in patients with osteosarcoma

•The apoptosis gene expression decreased in tumor tissues of osteosarcoma.•The Gpx4 expression decreased; while TfR1 increased in tumor tissues of osteosarcoma.•The apoptosis and ferroptosis mediator’s expression pattern was correlated with tumor severity, grade, tumor metastasis