Redox/pH-dual responsive functional hollow silica nanoparticles for hyaluronic acid-guided drug delivery

Donghun Shin,Seungki Lee,Hyun Sung Jang,Ji Bong Joo,Inhee Choi

Journal of Industrial and Engineering Chemistry（2022）

引用 16|浏览1

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摘要

•HMSN-SS-HA achieved high drug loading efficiency of 96% and minimized drug leakage.•Functional HMSNs accelerated the drug release kinetics under redox/pH-dual stimuli.•HA capping allowed cancer cell targeting via CD44 receptor-mediated recognition.

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关键词

Hollow mesoporous silica nanoparticle,pH responsive,Redox responsive,Hyaluronic acid,Drug delivery,CD44 receptor

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