Review on Microbial Bioinformatics: Novel and Promoting Trend for Microbiomics Research and Applications

The recent biotechnological advances and the rapid development of next-generation sequencing technologies accompanied by efficient computational facilities and tools have led to explosive and extensive data generation from finished complete genomes and draft genomes, because of this development, an urgent need arises for fast computing and automated approaches to analyze these bio big-data issued from microbial genomes and metagenomes in effective and a comparative way. Bioinformatics has come to play this major role via microbial bioinformatics and microbiomics which fill in the gap between just data accumulation and theoretical speculations to solution discovery and ready for use applications. In this perspective, our review gives an overview on microbial bioinformatics disciplines and subdisciplines and surveys their items, roles, influencing technologies and challenges, as well as lists the most microbial bioinformatics and metagenomics online resources, assemblers, and software, Furthermore, summarizes all the possible biotechnological applications of microbial bioinformatics and microbiomics in agriculture, food, medicine, industry, energy, and environment.