Recent Advances in Electrochemical C(3)-H Functionalization-2(1H)-ones

Quinoxalinone and its derivatives are a class of important nitrogen heterocyclic compounds, which widely exist in natural products, drugs and functional materials. Therefore, the C II fmictionalization of quinoxalinorie has attracted extensive attention of chemical workers. In recent years, electrochemical synthesis directly uses electron as a "clean reagent" to participate in redo)c reaction without additional redox reagent, which has the characteristics of mild reaction conditions and good atom economy. This method meets the requirements of green chemistry and sustainable development. With the in-depth study on the mechanism of electrochemical synthesis and the standardization of reaction equipment, this method has become a powerful tool for functionalization of quinoxalitreones. The recent advances in the electrochemical;C(3) H functionalization of quinoxaline-2(11-I)-one are summarized. The reaction transformation conditions and mechanisms are systematically discussed' and the challenges and future directions of this field are included.