Self-Assembled Synthesis and Characterization of Novel [Co(1-vinylimidazole)(6)](center dot)NO3 Polymer: Highly Efficient Antimicrobial Agent

Cobalt coordination polymer i.e. [Co(1-VI)(6)]center dot NO3 was successfully synthesized with cobalt metal and (VI = vinylimidazole) and characterized by elemental analysis, FTIR, UV/Vis spectroscopy and X-ray crystallography. The structure of the compound was determined by single X-ray crystallography at temperature 296 K with a Bruker APEX II CCD diffractometer using Mo-K alpha radiations (lambda = 0.71073 angstrom), R = 0.0642 and 0.0989. Orthorhombic unit cell parameters are a= 16.1341 (6) angstrom, b = 16.5179(16) angstrom, c = 18.2664(16) angstrom, V= 4868.0 (8) angstrom, Dx = 4, Mr = 937.91. The X-ray crystallography studies showed that the compound is polymeric in nature, in which cobalt atom coordinated with six N atoms of the 1-vinylimidazole ligands in a distorted orthorhombic geometry. As-prepared compound was screened in vitro against a variety of microorganisms, such as Gram-positive (G +ve) Staphylococcusaureus (S. aureus) and Gram-negative (G -ve) Escherichia coli (E. coli) bacterial strains, and fungal species with Aspergillus niger (A. niger) and Rhizopus stolonifer(R.stolonifer)by applying disk diffusion method. MIC (minimum inhibitory concentration) value for prepared [Co(1-VI)(6)]center dot NO3 compound is 125 mu g.mL(-1 )a this MIC value cobalt polymer showed higher activity against E. coli and S. aureus () as compared to fungi including; R. StoloniferandA. Niger at 125 mu g.mL(-1)).This study helps to reduce the risk of infectious diseases caused by various microorganisms.