PET Imaging of Leg Arteries for Determining the Input Function in PET/MRI Brain Studies Using a Compact, MRI-Compatible PET System

Shouyi Wei,Nandita Joshi,Michael Salerno,David Ouellette,Lemise Saleh,Christine Delorenzo,Craig Woody,David Schlyer,Martin L. Purschke,Jean-Francois Pratte,Sachin Junnarkar,Michael Budassi, Tuoyu Cao,Jack Fried,Joel S. Karp,Paul Vaska

IEEE Transactions on Radiation and Plasma Medical Sciences（2022）

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摘要

In this study, we used a compact, high-resolution, and magnetic resonance imaging (MRI)-compatible positron emission tomography (PET) camera (VersaPET) to assess the feasibility of measuring the image-derived input function (IDIF) from arteries in the leg with the ultimate goal of enabling fully quantitative PET brain imaging without blood sampling. We used this approach in five 18F-FDG...

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关键词

Blood,Positron emission tomography,Legged locomotion,Imaging,Arteries,Biomedical engineering,Spatial resolution

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