Hepatocellular carcinoma (HCC) in a patient with cystic fibrosis and liver disease (cirrhosis)

Nowadays, cystic fibrosis is a disease in which, due to early diagnosis and advances in treatment, the age limit has been considerably extended, resulting in many patients living beyond the fourth decade of life. However, due to increased life expectancy, the risk of developing diseases due to chronic complications and pathophysiology of cystic fibrosis has increased. The case of a male patient with cystic fibrosis and documented liver disease related to the primary disease is described. When the annual liver ultrasound was performed, masses of a heterogeneous echostructure in the right lobe of the liver were visualized. A three-phase liver computed tomography followed, showing a space-occupying lesion, which ultimately proved to be a hepatocellular carcinoma. It is worth mentioning that while one of the rare complications of liver cystic fibrosis disease is cholangiocarcinoma, this patient developed a hepatocellular carcinoma.