GP13, an Arthrospira platensis cysteine desulfurase-derived peptide, suppresses oxidative stress and reduces apoptosis in human leucocytes and zebrafish (Danio rerio) embryo via attenuated caspase-3 expression

Arthrospira platensis (Ap) has several advantageous adaptive mechanisms including its efficient response to elevated oxidative stress (OS). This study intends to identify the antioxidant effect, in vitro and in vivo, of a novel peptide (GP13), Ap-derived cysteine-desulfurase (CDS) peptide, for antioxidant role and the associated mechanism(s) by which the GP13 elicits cytoprotection under elevated OS.