Stereoselective Cycloaddition of Alkanesulfonyl Chlorides to Dihydroberberine

E. D. Gladkova,O. A. Luzina,N. F. Salakhutdinov

CHEMISTRY OF NATURAL COMPOUNDS（2021）

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摘要

Novel berberine derivatives with annelated four-membered sulfone rings were synthesized. Cycloaddition of alkanesulfonyl chlorides to dihydroberberine occurred with high stereoselectivity and formed a single stereoisomer.

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关键词

berberine,dihydroberberine,alkanesulfonyl chloride,sulfone,cycloaddition

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