Analysis of Commercial Fluoride-containing Mouthwashes for Children Using Nuclear Magnetic Resonance Spectroscopy

Most fluoride-containing mouthwashes for children have flavors and fragrances added to them, so you need to be careful about swallowing accidents. It is also necessary to check the amount of fluoride remaining in the oral cavity after using them. Therefore, this study compared whether the total fluoride (TF) of three types of children's mouthwash commercially available in Korea is compatible with the standards indicated by manufacturers. In addition, the amount of fluoride remaining in the saliva of the oral cavity after using mouthwash was confirmed through Fluorine (F-19) Nuclear magnetic resonance (NMR) spectroscopy. As a result, even fluoride in Garglin Kids Care was marked as 226.1 ppm but detected TF was at an average of 455.818, which was about 102 % more. The fluoride remaining in saliva after 1 minute of using mouthwash was 0.0144 % for 2080 Kids, 15.4477 % for Chikachika, and 0.0015 % for Garglin Kids Care. After 2 minutes of using mouthwash, very little fluoride was present in the oral saliva in all three types of mouthwashes. These results confirmed that mouthwash containing fluoride for children does not affect the human body, such as toxicity. Therefore, the safe use of mouthwashes can lead to the improvement of oral health in children.