Mining protein fibrils using structural biology

Hideyuki Takahashi,Stephen M. Strittmatter

NATURE（2022）

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摘要

Protein fibrils accumulate in the brain during neurodegeneration. Cryo-electron microscopy has now uncovered fibrils of a protein not previously thought to accumulate. High-resolution structures of TMEM106B fibrils.

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关键词

Neurodegeneration, Structural biology

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