Ustekinumab Trough Concentrations Associated with Biochemical Outcomes in Patients with Crohn's Disease

T. Straatmijer,V. B. C. Biemans,D. J. A. R. Moes,F. Hoentjen,R. ter Heine,P. W. J. Maljaars,R. Theeuwen,M. Pierik,M. Duijvestein,A. E. van der Meulen

JOURNAL OF CROHNS & COLITIS（2022）

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摘要

In this real-world cohort of patients with CD, UST levels in the highest quartile (≥ 6.3 µg/mL) at week 8 were associated with higher biochemical remission rates at week 24.

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关键词

Crohn’s disease,Inflammatory bowel disease,Pharmacokinetics,Ustekinumab

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