Polycrystalline simulations of in-reactor deformation of recrystallized Zircaloy-4 tubes: Fast Fourier Transform computations and mean-field self-consistent model

•Fast Fourier transform simulations have been conducted on large grain aggregates to simulate the in-reactor behavior of recrystallized of zirconium alloys.•The local constitutive behavior takes into account the evolution of irradiation defects and especially c-loops.•The model is adjusted on irradiation creep tests and the macroscopic irradiation growth is correctly predicted from the irradiation defects evolution.•A quantitative relationship between the microstructure of c-loops and growth strain is achieved for the first time.