Selective Separation of no Carrier added Sc-47 from Reactor Irradiated Ca Using Zirconium Vanadate Gel for Nuclear Medical Applications

Various concentrations of HCl or HNO3 on Zirconium Vanadate (ZrV) gel as an ion exchanger were studied by batch technique to determine the K-d values of Ca-47(II) and Sc-47(III) ions. A small chromatographic column packed with ZrV gel for Sc-47(III) separation based on a high elution yield with high purity from the point of view chemical, radiochemical and radionuclidic. The maximum elution yield of Sc-47 (88 +/- 2.2%) was obtained using 60% acetone-0.2 M HCl as an eluent. The Sc-47 was separated with acceptable radionuclidic purity (> 99.98 +/- 0.001%) and radiochemical purity (99.9 +/- 0.09%), in addition to a very low concentrations of Ca+2 ( 0.05 ppm) which is lower than the permissible level (10 ppm) for medical applications, particularly for the labelling of pharmaceutical compounds.