CKD-MBD biomarkers and CKD progression: an analysis by the joint model.
NEPHROLOGY DIALYSIS TRANSPLANTATION(2023)
摘要
Repeated measurements of serum PTH, calcium and phosphate as well as baseline FGF23 and 1,25-dihydroxyvitamin D are independently related with the progression to kidney failure in a cohort of stage 2-5 CKD patients. This longitudinal study generates the hypothesis that interventions at multiple levels on MBD biomarkers can mitigate renal function loss in this population.
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关键词
1,25-dihydroxyvitamin D,CKD,CKD-MBD,FGF23,PTH,alkaline phosphatase,calcium,kidney failure,phosphate
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