Novel biosynthesis of Ag-nanocomplex for controlling Verticillium wilt disease of olive tree

The nano-metal complexes are found to be more impregnable than their parent drugs, therefore this study was aimed to synthesize Ag-nanocomplex of paracetamol (Para) by novel biosynthesis method. Paracetamol Ag-nanocomplex with the formula [Ag(Para)(2)(NO3)(2)] has been characterized and synthesized on the basis of elemental analysis, thermal (TGA), conductivity, H-1, C-13 NMR and electronic spectral studies. Verticillium wilt, caused by Verticillium dahliae is considered one of the most serious diseases in olives. The use of Ag-nanocomplex as antifungal with different concentration (25, 50, 100 and 150 mg/ml) led to significant reductions of forming colonies of Verticillium wilt pathogenic fungi, with efficiencies reaching to 79.4, 82.9 and 81.8%, respectively at (100 mg/ml) against "V. dahliae, Fusarium acuminatum and Alternaria brassicae" LD50 was also evaluated, while no changes in physical activity were detected, so this research opens outlooks for more study of fungal biogenic nanoparticles, indicating their use for controlling an agricultural pests