Modification of magnetite-doped NH2-MIL-100(Fe) with aliphatic C8 carbon chain for feasible protein purification in reversed-phase mode

Chung-Hui Hsu,Yu-Sheng Yu,Yesong Gu,Kevin C. W. Wu

Separation and Purification Technology（2022）

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摘要

•A novel NH2-MIL-100(Fe)-C8 is made for protein separation in reversed-phase mode.•It has a binding specificity of 6.25 μg of BSA/mg particle.•It provides a good resolution for protein separation.•It can be regenerated over 15 times and maintain a high protein capacity.

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关键词

Magnetic Metal-Organic Framework composite,aliphatic C8 carbon chain,Reversed-phase mode,Protein separation and purification

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