Update S3-Guideline Irritable Bowel Syndrome: Definition, Pathophysiology, Diagnosis and Therapy. Joint Guideline of the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS) and the German Society for Neurogastroenterology and Motility (DGNM) - June 2021 - AWMF Registration Number: 021/016 (vol 59, pg 1323, 2021)