Spectroscopic identification of histamine using metalloporphyrins and their electrochemical characterization

Due to their 7-extended conjugated electronic system, porphyrins are excellent candidates for sophisticated energy transfer devices, including sensors. Their versatile optical and photochemical behaviour have eased the functionalization of porphyrins and their derivatives with different molecules, antenna-like sensors capable of identifying down to ppb levels of analytes. In this study, we present the spectroscopic identification of histamine using Zn-porphyrin and the electrochemical behaviour of Co- and Mn-porphyrins immobilized by dropcasting onto carbon-based screen-printed electrodes (SPEs). The cyclic voltammetry studies performed on the three metalloporphyrins showed different behaviours towards histamine detection, particularly in the presence of trichloroacetic acid, used as reaction mediator.