Synthesis and properties of Tetraaryl-1,8-naphthyridines

1,8-Naphthyridines are previously showed various biological activity and have been employed in su-pramolecular chemistry. We herein report the synthesis of formerly unknown 3,6-dibromo-2,7-dichlorotetrahaphthyridine and its employment in by Palladium catalysed Suzuki-Miyaura reaction. Synthesized 2,3,6,7-tetraarylnaphthtyridines have been obtained in generally good to excellent yields. The impact of donor-and acceptor substituents as well as the influence of acid on the optical properties have been studied by steady-state UV/Vis-and fluorescence spectroscopy and further analysed by cyclovoltammetry and DFT-calculations. (c) 2021 Elsevier Ltd. All rights reserved.