Development of Zika NS1 ELISA methodology for seroprevalence detection in a cohort of Mexican patients in an endemic region

Journal of Clinical Virology Plus(2021)

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摘要
•ELISA assay based on Zika NS1 antigens has a high sensitivity comparable to a commercial kit.•NS1 based ELISA in this study is rapid and easy to use for the diagnosis of Zika infection.•NS1 β-ladder based ELISA may increase the sensitivity and reduce the production cost making it suitable for use in arboviral endemic regions in resource-limited settings.
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关键词
Zika virus,NS1,Diagnosis,ELISA,Febrile patients,ZIKV antibodies,Mexico,Zika antibodies
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