Biomarkers in the diagnosis of wounds infection: An analytical perspective

Infection is one of the most serious complications that can occur in wounds. Biomarkers can be used as a tool directly related to infection. So, herein current methods and new approaches for the determination of wound infection, based on biomarkers, were compared and discussed. In this review, it is highlighted the different enzymatic biomarkers related to wound infection, and how they can be used for early detection of the same. It also aims to compile the different analytical methods and describe the potential of each one. The global and critical analysis research made it possible to perceive that of all the biomarkers studied, the enzymes demonstrated great potential, through the comparison with all biomarkers, since they allow the detection of infection in very early stages, and so a previous diagnostic and treatment. (C) 2021 Elsevier B.V. All rights reserved.