A case of neurobrucellosis detected during brucella treatment

Pinar Korkmaz, Irem Yildirim, Fatma Akkoyun Arikan,Halil Aslan,Duru Mistanoglu ozatag,Ozlem Genc, Mehmet Karaman

ANNALS OF CLINICAL AND ANALYTICAL MEDICINE(2021)

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摘要
Brucellosis is a systemic zoonotic infectious disease caused by the gram-negative Brucella bacteria that can be transmitted from infected animals to humans. Neurobrucellosis occurs when the central nervous system is directly or indirectly affected by Brucella spp. Clinical meningoencephalitis in neurobrucellosis includes meningovascular involvement, parenchymal dysfunction, peripheral neuropathy/radiculopathy, and various degrees of behavioral abnormalities. At the admission of our case, psychiatry was consulted considering psychosis due to decreased speech and agitation, there were no signs of meningeal irritation in physical examination, and no cells were seen in the first CSF examination. In the presence of unexplained neurological and psychiatric symptoms, especially in endemic areas, neurobrucellosis should be considered in the differential diagnosis, and necessary blood and CSF tests should performed.
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关键词
Meningoencephalitis, Brucellosis, Neurobrucellosis
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