Patterns of recurrence and prognosis in pathologic stage I and II Merkel cell carcinoma: A multicenter, retrospective cohort analysis

Andrew D Tieniber,Adrienne B Shannon,Michael J Carr,James Sun,Karenia Landa,Kirsten M Baecher,Kevin Lynch,Harrison G Bartels,Robyn Panchaud,Michael C Lowe,Craig L Slingluff,Mark J Jameson,Kenneth Y Tsai,Mark B Faries,Georgia M Beasley,Vernon K Sondak,Giorgos C Karakousis,Jonathan S Zager,John T Miura

Journal of the American Academy of Dermatology（2023）

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摘要

To the Editor: Merkel cell carcinoma (MCC) is a rare neuroendocrine skin tumor with a high risk of local and distant spread. Despite the increase in the use of sentinel lymph node biopsy as a result of recent National Comprehensive Cancer Network recommendations, there remains a paucity of data regarding outcomes in patients with clinically localized MCC with complete pathologic nodal microstaging.1 In MCC, disease relapse is a poor prognostic sign and efforts to prevent recurrences may result in improved survival.

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Merkel cell carcinoma,oncology,pathologic stage,prognosis,recurrence,SLNB,surgery

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