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Design and Synthesis of Tranylcypromine-Derived LSD1 Inhibitors with Improved Herg and Microsomal Stability Profiles

Yasuko Koda,Shin Sato,Hirofumi Yamamoto,Hideaki Niwa,Hisami Watanabe,Chiduru Watanabe,Tomohiro Sato,Kana Nakamura,Akiko Tanaka,Mikako Shirouzu,Teruki Honma,Takehiro Fukami,Hiroo Koyama,Takashi Umehara

ACS MEDICINAL CHEMISTRY LETTERS（2022）

Cited 5|Views18
Key words
Chromatin,Drug discovery,Epigenetics,Histone,Nucleosome
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