Global functioning, cognitive function, psychopathological symptoms in untreated patients with first-episode schizophrenia: A cross-sectional study

•This cross-sectional study with relatively large sample size found that patients with untreated first-episode schizophrenia had low global functioning by the GAF.•Pearson correlation analysis revealed that the GAF was positively associated with the MCCB and its six domains, while negatively associated with the PANSS and its four dimensions.•The study found that the negative symptom factor, the positive symptom factor, the excitement hostility factor, and attention/vigilante were all independent risk factors for global functioning in untreated first-episode schizophrenia.