ALYREF associated with immune infiltration is a prognostic biomarker in hepatocellular carcinoma

•ALYREF is a potential prognostic marker for hepatocellular carcinoma.•ALYREF affects the biological function of hepatocellular carcinoma cells.•ALYREF is associated with immune infiltration in hepatocellular carcinoma.•The model constructed based on ALYREF-related immune genes provides a reference for the evaluation of immunotherapy.