Synthesis, Characterisation and Antimicrobial Evaluations of Acetyloxyphenyl-1,2,3-triazole Linked Hexahydro Acridinediones

Journal of pharmaceutical research international(2022)

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摘要
10-(2-hydroxyphenyl)-hexahydro acridinediones were treated with chloroacetyl choloride to give 10-(2-chloroacetyloxyphenyl) hexahydro acridinediones, which were treated with NaN3 in acetone followed by reaction with DMAD yielded 10-[2-(1-triazolo-4,5-dicarboxymethyl)acetyloxyphenyl]-3,4,6,7,9,10-hexahydro-1,8-(2H,5H)- acridinediones.
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