A real-life multicenter study on the treatment of locally advanced Merkel cell carcinoma

Piotr Rutkowski,Monika Dudzisz-Śledź,Pawel Sobczuk,Katarzyna Kozak,Tomasz Switaj,Hanna Kosela-Paterczyk,Anna Malgorzata Czarnecka,Slawomir Falkowski,Pawel Rogala,Tadeusz Morysinski,Mateusz Spalek,Marcin Zdzienicki,Tomasz Goryn,Marcin Zietek,Bozena Cybulska-Stopa,Stanislaw Klek,Grazyna Kaminska-Winciorek,Barbara Ziolkowska,Anna Szumera-Cieckiewicz

Ejso（2022）

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摘要

Background: Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer with a high risk of recurrence and poor prognosis. Treatment should be carried out in specialized centers in experienced multidisciplinary teams. The basis of treatment of locally advanced MCC (laMCC) is surgery (SUR). In cases without clinical lymph node (LN) involvement, the sentinel lymph node biopsy (SLNB) is recommended. Radiotherapy (RTH) may be an alternative to SUR in some pts and may be considered in the perioperative setting.

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