Adenovirus-Associated Uveitis with Necrotizing Retinitis: Clinical Features and Genetic Analysis, a New Disease Entity

Sunao Sugita,Yoshihiko Usui,Hidemi Watanabe, Laura Panto, Miyabi Iida, Keisuke Suginoshita,Kanako O. Koyanagi,Akihiro Nishida,Yasuo Kurimoto,Masayo Takahashi,Tatsuya Shindo,Hiroaki Nishioka, Masahiko Takano,Takeshi Kezuka,Hiroshi Goto,Nobuyoshi Kitaichi

Social Science Research Network（2022）

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摘要

Infectious uveitis accounts for approximately 20% of uveitis cases, and 40% are idiopathic among all uveitis cases in Japan. 1 Ohguro N. Sonoda K.H. Takeuchi M. et al. The 2009 prospective multi-center epidemiologic survey of uveitis in Japan. Jpn J Ophthalmol. 2012; 56: 432-435 Crossref PubMed Scopus (186) Google Scholar ,2 Sonoda K.H. Hasegawa E. Namba K. et al. Epidemiology of uveitis in Japan: a 2016 retrospective nationwide survey. Jpn J Ophthalmol. 2021; 65: 184-190 Crossref PubMed Scopus (36) Google Scholar Even with the development of molecular biology–based diagnostic techniques, including polymerase chain reaction (PCR), it is still unclear whether some cases of uveitis of unknown etiology are caused by pathogens or not.

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关键词

Genome sequence,Human adenovirus,Infection,Polymerase chain reaction,Uveitis

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