Retinal changes in bipolar disorder as an endophenotype candidate: Comparison of OCT-detected retinal changes in patients, siblings, and healthy controls

Batuhan Ayık,Hatice Kaya,Rumeysa Tasdelen,Neslihan Sevimli

Psychiatry Research（2022）

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摘要

•OCT detects retinal changes reflecting neurodegeneration.•OCT findings found thinning of the retinal layers in BD patients.•RNFL thicknesses did not differ between patient, sibling and control groups.•GCL+IPL thickness may be a suitable endophenotype candidate for BD.

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关键词

Bipolar disorder,Endophenotype,OCT,Retina,Single-layer analysis

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