Estrogen Sulfotransferase is Required for the Female Mice Sensitivity to T Cell-Mediated Hepatitis in an Estrogen-Independent Manner.

Jingyuan Wang,Jibin Guan,Ziteng Zhang,Wen Xie

FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）

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摘要

Hepatic EST is required for female sensitivity to Con A-induced T-cell mediated hepatitis in an estrogen-independent manner. Pharmacological inhibition of EST might be a potential strategy for the treatment of AIH.

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