Glutathione Regulates Endothelial Cell Function and VEGFR2 Signaling.

Nabil A Rashdan,Ryan P Mackay,Luisa F Delgadillo,Christopher B Pattillo

FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）

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摘要

Combined these data suggest Src mediates the 2-AAPA + H O activation of VEGFR2. And that glutathionylation is necessary for this effect, co-immunoprecipitation experiments are underway to determine the glutathionylation status of Src in our system and its effect on the interaction of Src and VEGFR2.

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关键词

Arteriogenesis, Endothelial function, Redox

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