Time-dependent Characterization of Respiratory Parameters post Bleomycin-induced Lung Injury.

Nikolay Karpuk,Kajal Kamra,Steven J Lisco,Irving H Zucker,Hanjun Wang

FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）

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摘要

These data suggest that a single intratracheal instillation of Bleo induced long-lasting changes in respiratory function from acute to recovery phase of lung injury. Although blood gas returned to the normal level at W4 post Bleo, many respiratory parameters remained abnormal, indicating that pulmonary function might require a longer time to recover in this model.

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