Effect of Pulmonary Hypertension on Biaxial Viscoelastic Properties of the Right Ventricle at Rest and Exercise Conditions.

Wenqiang Liu,Kristen LeBar,Kellan Roth,Matt Ahern,Erith Evans,Jassia Pang,Jessica Ayers,Adam Chicco,Zhijie Wang

FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）

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摘要

This is the first report of RV biaxial viscoelasticity changes with PH in rats. In the diseased RV, increased viscoelasticity and altered anisotropy and viscoelasticity type were observed, and the viscoelasticity was reduced during exercise. These novel findings improve our understanding of RV biomechanics in response to pulsatile mechanical loadings at rest and exercise conditions.

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关键词

pulmonary hypertension,biaxial viscoelastic properties,right ventricle,exercise conditions

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