iTRAQ proteomics of sentinel lymph nodes for the identification of extra cellular matrix protein signatures that can flag metastasis in early breast cancer.

Gururao Hariprasad,Sheetal Pathania,Sabyasachi Bandyopadhyay,Piyush R Mishra,Sandeep Mathur,Smriti Hari

FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）

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摘要

Identified protein biomarkers have requisite diagnostic parameters to be developed as a translational tool to assess the status of sentinel lymph nodes during mastectomy procedure to guide surgical therapy of axillary lymph nodes in early breast oncology.

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