Endothelial Cell Sprouting in Coronary Collateral Growth.

Cody Juguilon,Anurag Jamaiyar,Weiguo Wan,James Gadd,Molly Enrick,Yang Wang,Alyssa Clark,William Chilian,Liya Yin

FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）

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摘要

- We developed a murine model of RI-induced coronary collateral growth, and our data show sprouting EC contribute to coronary collateral growth in adult hearts. Sprouting angiogenesis is shown for the first time to arterialize into mature blood vessels of larger diameter in response to repetitive ischemia in adult hearts.

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