Histone H3K27 Demethylase KDM6A Regulates Cardiac Aging viaInduction of HoxC4 mediated ER Stress.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）
摘要
Cardiomyocytes-specific conditional knockout of KDM6A causes cardiac aging through induction of HoxC4-mediated ER stress. These observations suggest KDM6A a potential therapeutic target for cardiac aging.
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