Functional Comparison of Human and Murine Equilibrative Nucleobase Transporter 1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）
摘要
Our results show that hENBT1 and mENBT1 are functionally similar in regards to ENBT1-mediated adenine and 6-MP transport in a stably transfected cell line. Additional work is necessary to investigate whether this is the case in human and murine hepatic cell lines/primary hepatocytes that have endogenous SLC43A3/ENBT1 expression and a larger range of xenobiotic metabolizing enzymes that may alter the equilibrium of 6-MP within cells.
更多查看译文
AI 理解论文
溯源树
样例
生成溯源树，研究论文发展脉络
Chat Paper
正在生成论文摘要