Influenza A Virus Causes Shedding of the Alveolar Epithelial Glycocalyx through Activation of Sheddases.

Kaitlyn R Schaaf, Charity J Buggs,Nathan D Putz,Christophe J Langouet-Astrie,Christopher S Jetter, Nicolas M Nigretti,Jennifer M S Sucre,Eric P Schmidt,Julie A Bastarache,Ciara M Shaver

FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）

引用 2|浏览3

暂无评分

摘要

Together, these data suggest that localized IAV infection increases MMP-7 in a murine model of IAV infection, but has no effect on several other sheddases. This suggests that MMP-7 may modulate IAV-induced glycocalyx shedding. Future studies will explore the mechanisms of IAV induced glycocalyx shedding which could provide molecular targets for clinical intervention in IAV-ARDS pathogenesis.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要