Depolarized Mitochondrial Membrane Potential and Protection with Duroquinone in Isolated Perfused Lungs from Rats Exposed to Hyperoxia.

Said Audi,Swetha Ganesh,Pardis Taheri,Xiao Zhang,Ranjan Dash,Anne Clough,Elizabeth Jacobs

FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）

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摘要

This study demonstrates hyperoxia-induced Δψ depolarization in isolated perfused lungs, and the utility of this approach for assessing the impact of potential therapies such as exogenous quinones that target mitochondria in isolated perfused lungs.

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Oxygen Saturation

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