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Development of a Commercial Process for Deucravacitinib, a Deuterated API for TYK2 Inhibition

Daniel S. Treitler,Maxime C. Soumeillant,Eric M. Simmons,Dong Lin,Bahar Inankur,Amanda J. Rogers,Michael Dummeldinger,Sergei Kolotuchin,Collin Chan,Jun Li,Adam Freitag,Federico Lora Gonzalez,Michael J. Smith,Chris Sfouggatakis, Jianji Wang,Tamas Benkovics,Joerg Deerberg,James H. Simpson,Ke Chen, Steven Tymonko

ORGANIC PROCESS RESEARCH & DEVELOPMENT（2022）

引用 19|浏览4
关键词
methyltriazole,EDC,HATU,PyBroP,POCl3,amidation
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