Theoretical Description for Dexketoprofen Electrochemical Determination, Assisted by VO(OH) Composite with Polypyrrole

An interesting electroanalytical process for dexketoprofen electrochemical determination over a polypyrrole-VO(OH)-modified electrode has been described. The electroanalytical process is realized by a cathodic reduction by two parallel mechanisms. The electroanalytical process kinetics is pH-dependent. The analysis of the mathematical model for this case has shown that the neutral and mildly acidic media is slightly more favorable to dexketoprofen electrochemical determination. The steady-state stability and electroanalytical efficiency of the process have been proven. The process may be used in vitro and in vivo to evaluate the drug delivery efficiency.