Design of microchannel to prevent C.elegans from running backwards

Hiromasa SHIGA,Toshio FUKUDA, Makoto KANEKO, Masaru TAKEUTI,Eunhye KIM

The Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec)(2021)

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摘要
In this study, we designed a microdevice that utilizes the chemotaxis of C. elegans. In previous studies, the device showed an increase in the locomotion speed of C.elegans, but the reverse locomotion of C.elegans was frequently observed. Therefore, in this study, we aim to improve the movement speed by designing the device to match the wavelength of the meandering motion of the nematode, and to fabricate a channel with a check valve so that we can easily check the number of individuals that showed an attraction response.
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microchannel
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