High-Resolution Structural MRI Suggests Protective Effects of Amygdala and Hippocampal Subregional Volume Following Traumatic Experiences

Biological Psychiatry(2022)

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摘要
The vast majority of individuals experience trauma within their lifetime. Yet, most people do not go on to develop clinical levels of psychopathology. Recently, studies have highlighted the potential protective effects of having larger amygdala and hippocampal volumes, such that larger volumes may promote adaptive functioning following trauma. However, research has not yet elucidated whether specific subregions of these stress-sensitive structures have specific protective effects.
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关键词
Hippocampus Subfields, Amygdala Subnuclei, Trauma Exposure, Structural Magnetic Resonance Imaging, Mediation Analysis
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