Preparation of photothermal-sensitive PDGF@ZIF-8-PDA@COL/PLGA-TCP composite scaffolds for bone defect repair

Tao Ni,Yiming Zhu,Liang Hao,Yu Chen,Tao Cheng

Materials & Design（2022）

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摘要

•Novel bioactive composite scaffold with capability to release loaded platelet-derived growth factor in sustained manner was prepared.•Prepared composite scaffolds exhibited in vitro antibacterial and osteoconductive activities.•In vivo accelerated formation of cranial bone with prepared composite scaffold established their possible application in clinical settings.

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关键词

Cranial defects,Photothermal,Growth factor,Composite scaffolds,Bone regeneration

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