Effects of Different Deep Brain Stimulation Frequencies on Lower Limb Movement in Patients with Parkinson's Disease

The effects of different deep brain stimulation (DBS) frequencies on lower limb movement in patients with Parkinson’s disease are not clear. In this study, we analyzed the clinical evaluation scores and biomechanical paraments in lower limb motor examinations under different DBS frequency settings. Both high-frequency and variable-frequency stimulations showed obvious improvements in motor symptoms. Considering the effectiveness in controlling axial symptoms, variable-frequency stimulation might be a potential stimulation setting in practice. Clinical Relevance—This study explores the effects of different DBS frequency settings on lower limb movement in patients with Parkinson's Disease.