SARS-CoV-2 seroprevalence in a rural and urban community household cohort in South Africa, after the third wave, April-November 2021

Jackie Kleynhans,Stefano Tempia,Nicole Wolter,Anne von Gottberg,Jinal N. Bhiman,Amelia Buys,Jocelyn Moyes,Meredith L. McMorrow,Kathleen Kahn,F. Xavier Gómez-Olivé,Stephen Tollman,Neil A. Martinson,Floidy Wafawanaka,Limakatso Lebina,Jacques du Toit,Waasila Jassat,Mzimasi Neti,Marieke Brauer,Cheryl Cohen

medRxiv（2022）

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摘要

By November 2021, after the third SARS-CoV-2 wave in South Africa, seroprevalence was 60% (95%CrI 56%-64%) in a rural and 70% (95%CrI 56%-64%) in an urban community; highest in individuals aged 13-18 years. High seroprevalence prior to Omicron emergence may have contributed to reduced severity observed in the 4th wave.

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