Chest CT Findings of COVID-19 Delta Variant in A Hospital Cluster

The B.1.617.2 (Delta) variant of the SARS-CoV-2 virus has been the cause of surging COVID-19 cases in many coun tries in recent months. We present a review of the CT chest imaging findings of eight patients from a hospital cluster, where the SARS-CoV-2 virus was diagnosed with Real-Time Polymerase Chain Reaction (RT-PCR) testing and confirmed by whole genome sequencing to be of the same Delta (B.1.617) variant strain. This case series highlights CT find ings considered atypical for COVID-19, but were observed in higher proportions than reported in the literature-spe -cifically, upper lobe predominance, unilaterality and pres ence of pleural effusions. We recommend larger scale in vestigation into the CT imaging phenotype of Delta variant infection to sharpen our ability to diagnose COVID-19 as the pandemic evolves.