Genome-wide association study of chronic sputum production implicates loci involved in mucus production and infection.

medRxiv（2023）

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摘要

Novel signals at the and mucin loci suggest that mucin fucosylation may be a driver of chronic sputum production even in the absence of diagnosed respiratory disease and provide genetic support for this pathway as a target for therapeutic intervention.

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关键词

chronic sputum production,mucus production,loci,genome-wide

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